920001 Molecular and Cellular Neuroscience

Sub-Exam 1 28.9.2016

1. Why is passive signal conduction inefficient in neurons? Please explain what is saltatory conduction and how the neurons benefit from it.

2. Which different types of “forces” regulate ion channel gating? What kind of structural features in the channels or accessory structures are these related to?

3. Describe the key molecular components of the postsynaptic density (PSD) and explain how they contribute to efficient signal transduction.

4. Explain the terms “associativity” and “input-specifity” in the context of LTP

Sub-Exam 2 28.10.2016

1. List the differet stages of neuronal development and compare the relative importance of genetic and environmental influences in each of the stages

2. How actin cytoskeleton and microtubules contribute to Growth Cone Motility?

3. What are the main intracellular signalling pathways activated by neutrophins and neurokines?