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Genome-environment interaction: DNA damage, individual susceptibility and cancer

17.5.2013

3 op

Answer all the questions.

  1. Significance of genotoxicity testing in genetic toxicology
  2. Compare the roles and significance of mutations and epigenetic changes in human carcinogenesis
  3. Explain how gene-environment interactions can affect the assessment of chemical exposures and the related disease risk
  4. Chromosomal aberrations in radiation dose estimation